In obesity and weight loss, all roads lead to the mighty macrophage.

نویسندگان

  • Alex Red Eagle
  • Ajay Chawla
چکیده

Obesity is associated with infiltration of white adipose tissue (WAT) by macrophages, which contributes to the development of insulin resistance. In this issue of the JCI, Kosteli and colleagues demonstrate that weight loss is unexpectedly also associated with rapid, albeit transient, recruitment of macrophages to WAT and that this appears to be related to lipolysis.

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عنوان ژورنال:
  • The Journal of clinical investigation

دوره 120 10  شماره 

صفحات  -

تاریخ انتشار 2010